HDL biology
Horses show no significant cholesteryl ester transfer protein activity despite having VLDL, LDL, and HDL (Comp Biochem Physiol B 1993)
Original title: Plasma lipid transport in the horse (Equus caballus)
This brief characterization of equine plasma lipid transport reports that horse plasma contains VLDL, LDL, and HDL, with HDL accounting for about 60% of plasma lipoprotein mass as a single particle population, while LDL is heterogeneous and comprises three discrete subfractions. Two proteins resembling apolipoprotein B-100 are found in VLDL and LDL, along with a third resembling apoB-48 in VLDL. Lecithin:cholesterol acyltransferase is active in horse plasma, and hepatic lipase and lipoprotein lipase are present in postheparin plasma, but there is no significant cholesteryl ester transfer protein activity in horses.
Original abstract
1. Equine plasma contains lipoproteins corresponding to very low density (VLDL), low density (LDL) and high density lipoproteins (HDL). 2. HDL accounts for approximately 60% of plasma lipoprotein mass and consists of a single population of particles. 3. LDL is heterogeneous comprising three discrete subfractions. 4. Two proteins are found in the region of apolipoprotein (apo) B-100 in VLDL and LDL and a third similar to apoB-48 is in VLDL. 5. Lecithin:cholesterol acyl transferase is active in plasma and hepatic lipase and lipoprotein lipase are evident in post-heparin plasma. 6. There is no significant cholesteryl ester transfer protein activity.
Summary written by cetpinhibition.org from the published abstract; figures as published. Page updated 19 August 2026. Methods.