HDL biology
A methods chapter frames CETP, also known as lipid transfer protein I, as the enzyme linking triglyceride-rich and cholesterol-rich lipoprotein metabolism (Methods Mol Med 2001)
Original title: 7 detecting cholesteryl ester transfer protein in plasma
This methods chapter introduces cholesteryl ester transfer protein (CETP), also referred to as lipid transfer protein I (LTP-I), as the plasma glycoprotein that links the metabolism of triglyceride-rich lipoproteins (chylomicrons and VLDL) with cholesterol-rich lipoproteins (LDL and HDL) via the exchange processes it catalyzes. The chapter frames CETP as the central mediator connecting these two major lipoprotein transport pathways in plasma, introducing the methods for detecting CETP in plasma that the chapter goes on to describe.
Original abstract
Transport of triglycerides (TGs) and cholesteryl esters (CEs) in plasma can be viewed as taking place via two major groups of lipoproteins, the TG-rich lipoproteins (chylomicrons and VLDL), on one hand, and the cholesterol-rich lipoproteins (LDL and HDL), on the other. The metabolism of these groups is linked by exchange processes, catalyzed mainly by a plasma glycoprotein referred to as lipid transfer protein I (LTP-I) (1) or cholesteryl ester transfer protein (CETP) (2-5).
Summary written by cetpinhibition.org from the published abstract; figures as published. Page updated 19 August 2026. Methods.