Pcsk9 9 items
Studies
- A 425,354-person UK Biobank Mendelian randomization study finds genetically lower CETP cuts coronary artery disease risk with additive benefit alongside PCSK9 (JAMA Cardiol 2022)
- Drug-target Mendelian randomization confirms CETP as an effective target for coronary heart disease with an on-target macular degeneration risk (Nat Commun 2021)
- Trivalent implant vaccine targets PCSK9, ApoB, and CETP as "cholesterol checkpoint" proteins (Adv Ther (Weinh) 2021)
- LDL receptor enables a CETP-independent route for macrophage cholesterol to reach faeces, mouse study finds (Circ Res 2020)
- Combining policosanol with 10-dehydrogingerdione strengthens CETP inhibition and lowers platelet activation in dyslipidaemic rabbits (Appl Biochem Biotechnol 2018)
- Adding torcetrapib to atorvastatin lowers lipoprotein(a) by 11 percent while modestly raising PCSK9, an ILLUMINATE biomarker substudy finds (J Clin Lipidol 2018)
- Circulating PCSK9 levels and CETP plasma activity are independently correlated in patients with metabolic disease (Cardiovasc Diabetol 2016)
- A review commits to covering PCSK9, ANGPTL8, sortilin and CETP as candidate molecular links between psoriasis and cardiometabolic syndrome risk (Int J Mol Sci 2020)
- Walnut kernel polyphenols are proposed to improve metabolic syndrome partly by inhibiting SREBPs, PCSK9 and CETP (Food Sci Nutr 2024)