Plaque imaging 28 items
Trials, agents, guidance
Studies
- HDL-cholesterol predicts carotid atherosclerosis only when CETP concentration is low, in the IMPROVE study (Biomedicines 2021)Biomedicines · March 2021 8
- The dal-PLAQUE imaging trial finds no evidence dalcetrapib harms the arterial wall after the failure of torcetrapib (Lancet 2011)Lancet · September 2011 8
- The ILLUSTRATE trial finds coronary atheroma regression on torcetrapib only in patients reaching the highest quartile of HDL-C rise (Circulation 2008)Circulation · November 2008 8
- Pooled RADIANCE trial data link the carotid-thickening harm of torcetrapib to a mineralocorticoid effect, not to its HDL-raising action (Circulation 2008)Circulation · November 2008 8
- The RADIANCE 2 trial finds torcetrapib raises blood pressure and HDL but does not slow carotid thickening in mixed dyslipidaemia (Lancet 2007)Lancet · July 2007 8
- The ILLUSTRATE trial finds no significant slowing of coronary atheroma progression from torcetrapib despite reaching an LDL-to-HDL ratio below 1.0 (N Engl J Med 2007)N Engl J Med · March 2007 8
- The RADIANCE 1 trial finds torcetrapib worsens common carotid thickening in familial hypercholesterolemia despite raising HDL to 81.5 mg per dL (N Engl J Med 2007)N Engl J Med · March 2007 8
- High baseline CETP predicts worse atherosclerosis progression on statins in familial hypercholesterolemia (Atherosclerosis 2004)Atherosclerosis · April 2004 8
- Plasma CETP concentration, not TaqIB genotype, predicts atherosclerosis progression and pravastatin benefit in REGRESS (Eur J Clin Invest 2004)Eur J Clin Invest · January 2004 8
- Pharmacogenomics review details how ADCY9 genotype determines the cardiovascular effect of dalcetrapib in dal-OUTCOMES (ATVB 2017)Arterioscler Thromb Vasc Biol · January 2017 7
- Higher CETP quartiles predict more coronary calcium and thicker carotid intima-media in Japanese men, independent of D442G genotype (Am J Cardiol 2009)Am J Cardiol · July 2009 7
- REMBRANDT trial design: 300 ASCVD patients to test whether obicetrapib plus ezetimibe shrinks coronary plaque on CT angiography (Am Heart J 2025)Am Heart J · July 2025 6
- CETP activity does not track carotid intima-media thickness once diabetes control is poor, unlike in well-controlled patients (Acta Diabetol 2019)Acta Diabetol · April 2019 6
- Mendelian randomization finds no overall causal link between genetically determined CETP and carotid intima-media thickness (J Clin Lipidol 2018)J Clin Lipidol · November 2017 6
- Familial hypercholesterolemia patients show elevated CETP-mediated cholesteryl ester transfer and defective reverse cholesterol transport (Arterioscler Thromb Vasc Biol 2011)Arterioscler Thromb Vasc Biol · April 2011 6
- CETP Ile405Val predicts carotid intima-media thickness in men but not women in the Stanislas Cohort (Clin Genet 2001)Clin Genet · May 2001 6
- HIV infection is associated with elevated plasma CETP and LCAT alongside low HDL, without one-year progression of subclinical atherosclerosis (Atherosclerosis 2013)Atherosclerosis · April 2013 5
- CETP and hepatic lipase gene variants interact to raise carotid atherosclerosis risk in 1,549-person SAPHIR cohort (Atherosclerosis 2011)Atherosclerosis · March 2011 5
- Two novel CETP nonsense mutations produce complete deficiency without coronary disease in a Greek pedigree (J Mol Med 2006)J Mol Med (Berl) · July 2006 5
- Case report finds significant coronary stenosis in a woman with CETP deficiency and HDL-C of 209 mg/dL (Circ J 2005)Circ J · May 2005 5
- Carotid imaging shows CETP loss-of-function carriers, unlike apoA-I or ABCA1 mutation carriers, have unaltered atherosclerosis progression (Curr Opin Lipidol 2005)Curr Opin Lipidol · April 2005 5
- Cholesterol efflux capacity, but not CETP-mediated cholesterol ester transfer, correlates inversely with peripheral plaque volume (Biomedicines 2023)Biomedicines · July 2023 4
- dal-PLAQUE substudy finds dalcetrapib did not affect progression of vascular calcification (J Am Coll Cardiol 2016)J Am Coll Cardiol · January 2016 4
- CETP I405V and Taq1B polymorphisms show inconsistent links to subclinical carotid atherosclerosis in Brazilians (Lipids Health Dis 2012)Lipids Health Dis · October 2012 4
- CETP TaqIB genotype shows no link to plaque composition or neointima after carotid endarterectomy, unlike hepatic lipase variant (Atherosclerosis 2005)Atherosclerosis · July 2005 4
- The dal-PLAQUE study is designed to track dalcetrapib effects on carotid plaque burden and inflammation with MRI and PET/CT (Am Heart J 2011)Am Heart J · August 2011 3
- RADIANCE 1 and 2 are designed to compare torcetrapib plus atorvastatin against atorvastatin alone in over 1,650 patients using carotid ultrasound (Curr Med Res Opin 2007)Curr Med Res Opin · April 2007 3