cetpinhibition.org

Trial

TANDEM

NewAmsterdam Pharma (obicetrapib + ezetimibe) · NCT06005597 · 1 March 2024

Status Completed September 2024

407 patients randomised to the obicetrapib and ezetimibe fixed-dose combination or its components, completed September 2024. The trial behind Evlarco, the combination product in the European filing.

The combination is the commercially interesting product: roughly 50% LDL-C lowering from a single daily tablet on top of a statin, in a class of patient who has usually already run out of oral options.

ClinicalTrials.gov

ezetimibeLDL and apoBobicetrapibphase 3

Page updated 18 August 2026.