LDL and apoB
Six weeks of endurance training lowers CETP activity regardless of egg intake in unfit adults (J Nutr Biochem 2008)
Original title: Habitual consumption of eggs does not alter the beneficial effects of endurance training on plasma lipids and lipoprotein metabolism in untrained men and women
In 12 healthy but unfit adults randomized to an egg-based (12 eggs per week) or no-egg eucaloric diet during a six-week endurance exercise training program, endurance training produced a significant 10% increase in HDL-cholesterol (P<.05), a 19% decrease in Apo B (P<.05), and a significant reduction in plasma CETP activity (P<.05) in both diet groups, with LDL-cholesterol falling 21% (P=.06). No effects of diet or diet-exercise interaction were observed on lipids or Apo B. Endurance training therefore improved the plasma lipid profile of previously unfit, normolipidemic subjects independent of dietary cholesterol intake from eggs.
Original abstract
Changes in plasma lipid and apolipoprotein profiles were evaluated in 12 healthy, unfit subjects (VO(2peak) 39.1+/-2.8 ml.kg(-1).min(-1); 5 women, 7 men) at baseline and following endurance exercise training. The exercise protocol consisted of a 6-week endurance exercise training program (4-5 days week(-1); 60 min.session(-1); > or =65% HR(max)). Subjects were randomly assigned to consume an egg- (n=6; 12 eggs.week(-1)) or no-egg (n=6; 0 eggs.week(-1))-based, eucaloric, standardized diet for 8 weeks. Both diets were macronutrient balanced [60% carbohydrate, 30% fat, 10% protein (0.8 g.kg(-1).day(-1))] and individually designed for weight maintenance. Plasma lipids were measured twice within the same week at baseline and following exercise training. At baseline, subjects were normolipidemic with values of 163.9+/-41.8, 84.8+/-36.7, 60.6+/-15.4 and 93.1+/-52 mg dl(-1) for total cholesterol, LDL cholesterol and HDL cholesterol and triglyceride concentrations, respectively. A two-way ANOVA was used to analyze diet and exercise effects and interactions. In both groups, endurance exercise training resulted in a significant 10% increase in HDL-C (P<.05), a 19% decrease in Apo B concentrations (P<.05) and reductions in plasma CETP activity (P<.05). Plasma LDL-C decreased by 21% (P=.06). No main effects of diet or interactions with plasma lipids or Apo B concentrations were observed. These data demonstrate that endurance training improved the plasma lipid profiles of previously unfit, normolipidemic subjects independent of dietary cholesterol intake from eggs.
Summary written by cetpinhibition.org from the published abstract; figures as published. Page updated 19 August 2026. Methods.