Metabolic syndrome 19 items

Studies

• CETP Taq1B B2 variant cuts metabolic syndrome risk by up to 57% in a large Austrian cohort (Obesity (Silver Spring) 2008)Obesity (Silver Spring) · January 2008 7
• CETP Taq1B genotype interacts with obesity in women and predicts small dense LDL in men in a 1029-person Austrian cohort (Biomed Pharmacother 2004)Biomed Pharmacother · December 2004 7
• Rare CETP missense variants are linked to male-specific metabolic syndrome across five ancestries, transethnic exome study finds (Genes Genomics 2022)Genes Genomics · April 2022 6
• GWAS of 10,093 Indians finds CETP the primary genetic locus for metabolic syndrome, with a seven-variant haplotype as the strongest signal (Biomolecules 2019)Biomolecules · July 2019 6
• Five of six CETP polymorphisms are linked to metabolic syndrome in Uyghur adults, with two protective haplotypes identified (Int J Environ Res Public Health 2017)Int J Environ Res Public Health · June 2017 6
• Metabolic syndrome raises serum CETP activity 38% alongside dysfunctional, antioxidant-depleted HDL (Int J Mol Med 2010)Int J Mol Med · January 2010 6
• Fenofibrate lowers CETP activity while raising PLTP activity, reshaping apoB-100 kinetics in metabolic syndrome (Clin Sci (Lond) 2006)Clin Sci (Lond) · September 2006 6
• CETP mass is elevated in men, but not women, with metabolic syndrome, and tracks inversely with LDL particle size in both sexes (Obesity 2006)Obesity (Silver Spring) · May 2006 6
• Circulating PCSK9 levels and CETP plasma activity are independently correlated in patients with metabolic disease (Cardiovasc Diabetol 2016)Cardiovasc Diabetol · August 2016 5
• CETP variant rs708272 nearly doubles metabolic syndrome risk in women from southwestern Mexico (Int J Mol Sci 2015)Int J Mol Sci · September 2015 5
• CETP is one of five gene loci with pleiotropic effects across metabolic syndrome components in over 15,000 African Americans (Circ Cardiovasc Genet 2014)Circ Cardiovasc Genet · July 2014 5
• Systematic review confirms the CETP Taq-1B minor allele is protective against metabolic syndrome, among only eight genetic associations that hold up (Obes Rev 2011)Obes Rev · July 2011 5
• CETP Taq1B B1B1 genotype is more common in Egyptian metabolic syndrome patients and tracks with lower HDL cholesterol (Diabetes Metab Syndr 2011)Diabetes Metab Syndr · December 2010 5
• CETP B1 allele raises metabolic syndrome risk specifically in Turkish women, large cross-sectional study finds (Anadolu Kardiyol Derg 2008)Anadolu Kardiyol Derg · October 2008 5
• A CETP variant predicts who loses the most weight with a digital lifestyle-modification program (Sci Rep 2023)Sci Rep · December 2023 4
• GWAS of 49,915 Koreans finds CETP among the lipid genes shared by metabolically unhealthy normal-weight and obese phenotypes (Sci Rep 2021)Sci Rep · January 2021 4
• CETP variant rs820299 nominally associates with metabolic syndrome and interacts with lifestyle factors in a Taiwanese replication study (Sci Rep 2016)Sci Rep · November 2016 4
• Review names CETP inhibitors among emerging HDL-targeted therapies for insulin resistance syndrome (Semin Vasc Med 2004)Semin Vasc Med · May 2004 4
• Only atorvastatin, not fenofibrate, lowers CETP activity in metabolic syndrome patients despite both lowering triglycerides (Diabetes 2003)Diabetes · March 2003 4