Obesity 27 items

Studies

• Chronic CETP deficiency disrupts adipocyte lipid storage, revealing a novel intracellular role for CETP (J Biol Chem 2007)J Biol Chem · May 2007 7
• Adipose-specific CETP expression alone lowers HDL cholesterol and shrinks adipocytes in mice (J Lipid Res 2006)J Lipid Res · June 2006 7
• CETP moves HDL lipids into adipocytes without receptors or endocytosis, overturning the prevailing uptake model (J Lipid Res 2004)J Lipid Res · July 2004 7
• Elevated CETP activity, correlated with low HDL, may explain reduced HDL cholesterol in obesity (Arterioscler Thromb 1994)Arterioscler Thromb · July 1994 7
• CETP expression rises with obstructive sleep apnoea severity in obese young rats (Sleep Breath 2024)Sleep Breath · November 2024 6
• Diet-induced weight loss fails to improve HDL cholesterol efflux or cholesteryl ester transfer in obese men (Atherosclerosis 2018)Atherosclerosis · April 2018 6
• CETP variant D442G raises HDL cholesterol nearly three times more in obese than normal-weight Chinese individuals (Obesity 2009)Obesity (Silver Spring) · May 2009 6
• CETP expression reverses the obesity caused by apolipoprotein CIII overexpression in transgenic mice (Int J Obes 2007)Int J Obes (Lond) · May 2007 6
• CETP B2B2 genotype protects against acute coronary syndrome only in normal-weight Greeks, not the overweight or obese (Hum Hered 2007)Hum Hered · January 2007 6
• CETP gene variants predict how much fat monozygotic twins gain during 100 days of deliberate overfeeding (Atherosclerosis 2008)Atherosclerosis · December 2006 6
• First CETP-specific antibody fragments enable a new quantification assay and link plasma CETP to body fat mass (Clin Chem Lab Med 2004)Clin Chem Lab Med · March 2004 6
• Increased CETP activity tracks with the atherogenic lipoprotein profile of obese children (Atherosclerosis 1997)Atherosclerosis · February 1997 6
• Children with obesity show reduced CETP activity alongside broader HDL antioxidant breakdown and higher oxidative stress (J Clin Lipidol 2026)J Clin Lipidol · November 2025 5
• Abdominal obesity combines with the CETP TaqIB variant to raise cholesterol in Mexican women (Lifestyle Genom 2023)Lifestyle Genom · January 2023 5
• CETP variant rs3764261 emerges as a lean-mass protective marker in a Pakistani obesity genetics cohort (PLoS One 2022)PLoS One · January 2022 5
• A novel anti-adipogenic role for CETP: it boosts brown fat activity and lipolysis to reduce body fat, across three animal models (Metabolism 2021)Metabolism · November 2020 5
• Roux-en-Y gastric bypass lowers CETP activity alongside other markers of HDL function in severe obesity (Obes Surg 2020)Obes Surg · October 2020 5
• CETP variant rs5882 interacts with monounsaturated fat intake to affect triglyceride levels in overweight and obese adults (Lifestyle Genom 2020)Lifestyle Genom · January 2020 5
• CETP variant rs1800777 is linked to greater fat mass, central obesity, and lower HDL cholesterol in obese adults (Endocrinol Diabetes Nutr 2018)Endocrinol Diabetes Nutr (Engl Ed) · January 2018 5
• CETP variant rs5882 G allele is linked to lower HDL cholesterol in obese and non-obese individuals alike (Gene 2015)Gene · January 2015 5
• Combining CETP B2B2 with an ABCA1 variant produces the largest HDL cholesterol gap seen in a Chinese cohort of nearly 1 mmol/L (Acta Cardiol 2011)Acta Cardiol · April 2011 5
• CETP Taq1B genotype only predicts HDL cholesterol in obese women with low fasting insulin (Atherosclerosis 2002)Atherosclerosis · June 2002 5
• A CETP variant predicts who loses the most weight with a digital lifestyle-modification program (Sci Rep 2023)Sci Rep · December 2023 4
• CETP variant rs708272 ranks among the top ten SNPs in a 24-gene model predicting childhood and adolescent obesity, alongside diet and gut microbiota (Sci Rep 2020)Sci Rep · May 2020 4
• CETP G allele carriers show distinct waist circumference and metabolic profiles, independent of glucose and lipid changes (Diabetes Res Clin Pract 2014)Diabetes Res Clin Pract · July 2014 4
• CETP TaqIB variant, unlike APOE4, shows no link to obesity or blood pressure in North Indian subjects (Mol Cell Biochem 2008)Mol Cell Biochem · May 2008 4
• CETP activity correlates with insulin resistance and leptin in obese subjects, but not independently of other factors (Metabolism 2007)Metabolism · November 2007 3