Kidney 22 items
Studies
- CETP renaissance: a review maps obicetrapib reach beyond LDL-C into dementia, glycaemic control, sepsis and kidney function (Curr Atheroscler Rep 2026)
- Post hoc BROADWAY/BROOKLYN analysis: obicetrapib attenuates kidney function decline, tracking with achieved HDL-C (Am J Prev Cardiol 2026)
- CETP activity rises 46% in nephrotic-range proteinuria, contributing to its atherogenic lipoprotein profile (Atherosclerosis 2001)
- Lipoprotein-bound free fatty acids drive elevated CETP specific activity in nephrotic syndrome (Arterioscler Thromb Vasc Biol 1997)
- Elevated LCAT and CETP activities help explain abnormal HDL composition in nephrotic-range proteinuria (Kidney Int 1993)
- Elevated plasma CETP correlates with cholesteryl ester-enriched VLDL and normalizes with corticosteroid treatment in nephrotic syndrome (J Lipid Res 1992)
- CETP variant rs1800777 predicts low HDL cholesterol and acute kidney injury risk during sepsis, replicated across two cohorts (Sci Rep 2018)
- High CETP is an independent negative determinant of LDL size and tracks with CAD prevalence in haemodialysis patients (Nephrology (Carlton) 2011)
- Reducing proteinuria lowers LDL cholesterol together with plasma CETP mass, but also lowers HDL cholesterol (Expert Opin Ther Targets 2009)
- Low serum albumin is the main driver of elevated CETP in children with active nephrotic syndrome (Clin Biochem 2007)
- CETP Taq1B B1 allele linked to worse lipid profile and higher blood pressure in kidney transplant patients (Transplant Proc 2006)
- Hepatic lipase TT genotype protects against vascular disease only in hemodialysis patients with high CETP levels (Kidney Int 2003)
- CETP activity exceeds that of adults and control children in kids on peritoneal dialysis for end-stage renal disease (Nephron 1996)
- A PBPK model correctly predicts higher exposure to the active thiol form of dalcetrapib in chronic kidney disease (Xenobiotica 2021)
- A structural-and-metabolic-network computational model predicts off-target causes of the hypertensive side effect of torcetrapib in kidney tissue (PLoS Comput Biol 2010)
- Neither high CETP activity nor low HDL cholesterol predicts cardiovascular events in stage V chronic kidney disease (Nephrol Dial Transplant 2008)
- Review attributes chronic renal failure's HDL disorders partly to elevated CETP activity (Am J Physiol Renal Physiol 2006)
- CETP D442G mutation more than doubles vascular disease prevalence in dialysis patients, but only when HDL cholesterol is already low (Kidney Int Suppl 1999)
- Vitamin E tocotrienol supplementation lowered CETP activity and improved lipids in chronic hemodialysis patients (Vasc Health Risk Manag 2013)
- CETP activity stays unchanged despite severely disrupted lipoproteins in Hantaan virus renal failure (BMB Rep 2010)
- LCAT and CETP activity track with disturbed HDL and triglyceride-rich lipoprotein composition after kidney transplant (Cell Biochem Biophys 2013)
- Plasma CETP and PLTP levels are unchanged in end-stage renal disease despite HDL abnormalities (Nephrol Dial Transplant 2009)