Women 81 items

Studies

• In female mice, CETP enables an estrogen-SHP pathway raising VLDL triglyceride production and, independently, an ERalpha pathway boosting liver fat oxidation (J Lipid Res 2016)J Lipid Res · June 2016 8
• CETP mutations that lower HDL cholesterol paradoxically cut ischemic heart disease risk 36% in women, Copenhagen City Heart Study finds (Circulation 2000)Circulation · October 2000 8
• Mendelian randomisation links genetically raised HDL and LDL cholesterol, including a CETP locus signal, to higher breast cancer risk (PLoS Med 2020)PLoS Med · September 2020 7
• Transgenic CETP expression nearly doubles run distance in obese female mice via increased muscle mitochondrial oxidative capacity and PGC-1alpha (PLoS One 2015)PLoS One · January 2015 7
• Dietary cholesterol dose-dependently drives osteoarthritis in CETP-humanised mice, and atorvastatin but not ezetimibe suppresses it despite similar cholesterol lowering (Ann Rheum Dis 2013)Ann Rheum Dis · April 2013 7
• Two linked CETP SNPs more than double the odds of fatty liver in adolescent girls, independent of adiposity (J Gastroenterol Hepatol 2012)J Gastroenterol Hepatol · September 2012 7
• CETP deficiency, not high CETP activity, impairs postprandial lipemia clearance and correlates with carotid atherosclerosis in women (Lipids Health Dis 2011)Lipids Health Dis · May 2011 7
• In the Hoorn Study, high CETP concentration more than triples cardiovascular disease risk in women with Type 2 diabetes, with no such association in men (Diabet Med 2007)Diabet Med · February 2007 7
• CETP Taq1B genotype interacts with obesity in women and predicts small dense LDL in men in a 1029-person Austrian cohort (Biomed Pharmacother 2004)Biomed Pharmacother · December 2004 7
• CETP B2B2 genotype raises HDL cholesterol and particle size specifically in women in the Columbia BioMarkers Study (Nutr Metab Cardiovasc Dis 2002)Nutr Metab Cardiovasc Dis · August 2002 7
• CETP genotype shapes which HDL subfractions rise with endurance exercise training (Metabolism 2002)Metabolism · June 2002 7
• CETP-HDL relationships differ by sex, and CETP genotype does not explain Israel's low population HDL levels (Atherosclerosis 2000)Atherosclerosis · August 2000 7
• New CETP promoter repeat marker links the gene to LDL particle size, triglycerides, and apoB in twins (Circulation 2000)Circulation · May 2000 7
• CETP TaqIB genotype raises HDL-cholesterol and lowers coronary disease only in men with type 2 diabetes (J Clin Endocrinol Metab 1999)J Clin Endocrinol Metab · October 1999 7
• CETP expression raises body metabolism and leanness in female mice during both cold exposure and thermoneutrality (FASEB J 2025)FASEB J · February 2025 6
• CETP variants show BMI-dependent associations with atherogenic lipids and glucose traits in gestational diabetes (J Matern Fetal Neonatal Med 2024)J Matern Fetal Neonatal Med · October 2024 6
• CETP damages perivascular fat function in male mice through oxidative stress and inflammation, but preserves it in females (Function (Oxf) 2024)Function (Oxf) · July 2024 6
• Time-restricted eating reduces atherosclerotic lesion size and inflammatory cell content in CETP-humanised mice during simulated shift-work (EBioMedicine 2023)EBioMedicine · June 2023 6
• A multiancestry Mendelian randomization study suggests CETP inhibition may protect against preeclampsia via HDL cholesterol (Hypertension 2023)Hypertension · March 2023 6
• Sex and BMI modify how much genetically lower CETP raises HDL-C and lowers LDL-C, though not cardiovascular outcomes (Genet Epidemiol 2023)Genet Epidemiol · January 2023 6
• Across 6,606 adults and multiple imaging-based fat measures, no association is found between body fat and serum CETP, challenging the adipose-tissue-as-CETP-source hypothesis (Atherosclerosis 2016)Atherosclerosis · January 2016 6
• The CETP B2 allele is linked to lower LDL cholesterol specifically in black, not white, South African women (Atherosclerosis 2015)Atherosclerosis · March 2015 6
• CETP concentration is elevated and inversely correlates with hemoglobin in women with iron deficiency anaemia (Clin Lab 2015)Clin Lab · January 2015 6
• CETP and APOE variants interact to raise hypertriglyceridemia risk in oldest-old Chinese women (Exp Gerontol 2014)Exp Gerontol · April 2014 6
• CETP deficiency linked to cardiovascular disease and stroke within a high-HDL syndrome, especially in women (Mol Genet Metab Rep 2014)Mol Genet Metab Rep · January 2014 6
• CETP I405V polymorphism is an independent risk factor for endometriosis in a case-control study of women (Gynecol Endocrinol 2013)Gynecol Endocrinol · July 2013 6
• CETP transgene protects obese female mice from insulin resistance via bile acid signalling (Mol Metab 2013)Mol Metab · January 2013 6
• Women with angina pectoris show enhanced CETP activity in both HDL and LDL alongside impaired HDL antioxidant enzymes (Int J Mol Med 2011)Int J Mol Med · December 2011 6
• CETP haplotype G raises early-onset heart-attack risk up to 6-fold in men, independent of HDL-C (Ann Hum Genet 2008)Ann Hum Genet · July 2008 6
• White women with a CETP -629 A/A genotype gain the most HDL cholesterol from 20 weeks of endurance training (Physiol Genomics 2007)Physiol Genomics · May 2007 6
• Higher CETP activity in Hispanic postmenopausal women tracks with abdominal fat, not ethnicity itself (Metabolism 2003)Metabolism · March 2003 6
• Bariatric-surgery weight loss of 28.7 kg lowers CETP mass 27% and activity 25% in morbidly obese women, alongside an increase in LDL particle size (Arterioscler Thromb Vasc Biol 2002)Arterioscler Thromb Vasc Biol · September 2002 6
• CETP activity does not predict LDL buoyancy in women, but CETP TaqIB genotype does predict CETP mass and HDL3 cholesterol (Arterioscler Thromb Vasc Biol 2002)Arterioscler Thromb Vasc Biol · April 2002 6
• Serum CETP concentration falls in postmenopausal Chinese women and correlates positively with estradiol, negatively with FSH (Clin Chim Acta 2001)Clin Chim Acta · December 2001 6
• Psyllium fiber lowers CETP activity 18% regardless of sex, while its triglyceride effects diverge by sex and menopausal status (Am J Clin Nutr 2001)Am J Clin Nutr · October 2001 6
• Clamp-induced suppression of CETP activity is unrelated to whole-body insulin sensitivity, exercise-training study finds (Metabolism 2001)Metabolism · July 2001 6
• CETP Ile405Val predicts carotid intima-media thickness in men but not women in the Stanislas Cohort (Clin Genet 2001)Clin Genet · May 2001 6
• CETP activity differences do not explain how margarine and butter diets change HDL cholesterol (J Lipid Res 2001)J Lipid Res · April 2001 6
• Serum CETP is higher in women and higher still in Chinese myocardial infarction and stroke patients than in healthy controls (Clin Chim Acta 2001)Clin Chim Acta · March 2001 6
• Estrogen raises LDL cholesterol and atherosclerotic lesions in apoB100xCETP transgenic mice without altering CETP activity (Arterioscler Thromb Vasc Biol 1999)Arterioscler Thromb Vasc Biol · June 1999 6
• CETP is expressed early in human preadipocyte-to-adipocyte differentiation, ahead of known adipogenic transcription factors (Atherosclerosis 1999)Atherosclerosis · February 1999 6
• Ovariectomy reduces CETP activity in liver and adipose tissue of transgenic mice, and hormone replacement fails to restore it (Metabolism 1998)Metabolism · September 1998 6
• Plasma triglyceride level, not dietary fat saturation, is the rate-limiting factor for CETP-mediated cholesteryl ester transfer in hypercholesterolemic women (Atherosclerosis 1996)Atherosclerosis · October 1996 6
• A palmitic acid diet raises CETP activity 12 percent more than a stearic acid diet in young women (Metabolism 1996)Metabolism · February 1996 6
• CETP mRNA abundance in human adipose tissue tracks membrane cholesterol content, not stored lipid droplet cholesterol (J Lipid Res 1995)J Lipid Res · December 1995 6
• LpA-I-associated CETP concentration is significantly higher in women than men, while hyperlipidemic men shift CETP toward LpA-I:A-II particles (J Lipid Res 1994)J Lipid Res · May 1994 6
• Endothelial dysfunction develops earlier in male than female CETP-humanised hyperlipidaemic mice, preceding atherosclerosis (Geroscience 2025)Geroscience · April 2025 5
• Mendelian randomisation finds genetically proxied CETP inhibition associated with lower uterine fibroid risk (Heliyon 2025)Heliyon · December 2024 5
• Mendelian randomisation finds genetically higher CETP levels associated with increased non-endometrioid endometrial carcinoma risk (Front Endocrinol 2024)Front Endocrinol (Lausanne) · January 2024 5
• The CETP rs708272 genotype predicts statin response only in women with hyperlipidaemia (Malays J Med Sci 2023)Malays J Med Sci · April 2023 5
• Abdominal obesity combines with the CETP TaqIB variant to raise cholesterol in Mexican women (Lifestyle Genom 2023)Lifestyle Genom · January 2023 5
• A trans-ancestry GWAS in pregnant women finds the CETP locus approaches genome-wide significance for HDL cholesterol (J Clin Lipidol 2023)J Clin Lipidol · November 2022 5
• The CETP TaqIB B1B2/B2B2 genotype raises the risk of fatty liver disease in Mexican women with gallstones (Metab Syndr Relat Disord 2023)Metab Syndr Relat Disord · October 2022 5
• The CETP rs5883 T allele is linked to higher HDL cholesterol and lower risk of low HDL in postmenopausal obese women (Eur Rev Med Pharmacol Sci 2021)Eur Rev Med Pharmacol Sci · November 2021 5
• Low CETP activity late in pregnancy, in mother and placenta alike, is linked to giving birth to small-for-gestational-age infants (Sci Rep 2021)Sci Rep · March 2021 5
• High-dose dietary inulin shifts gut bacteria and raises short-chain fatty acids without reducing cholesterol or atherosclerosis in CETP-humanised mice (Sci Rep 2018)Sci Rep · November 2018 5
• Basal-bolus insulin lowers maternal triglycerides in gestational diabetes without changing CETP activity (J Obstet Gynaecol Res 2017)J Obstet Gynaecol Res · July 2017 5
• CETP variant rs1800775 is associated with HDL cholesterol and total cholesterol, but not LDL, in pregnant Chinese women (J Clin Lipidol 2017)J Clin Lipidol · January 2017 5
• Six months of aerobic exercise raises oxidized-HDL levels in women without any change in CETP or adiponectin concentration (Free Radic Res 2016)Free Radic Res · January 2016 5
• A Filipino GWAS finds suggestive CETP and TOM1 associations with HDL cholesterol and allelic heterogeneity at the CETP locus (J Lipid Res 2013)J Lipid Res · September 2013 5
• CETP and LPL polymorphisms jointly predict cardiovascular risk in women with high HDL cholesterol and CRP (Atherosclerosis 2011)Atherosclerosis · November 2010 5
• CETP TaqIB significantly shapes baseline HDL subpopulation profile in postmenopausal women, though hormone therapy response is largely unaffected (Clin Endocrinol 2010)Clin Endocrinol (Oxf) · May 2009 5
• CETP gene is the only lipid-metabolism gene whose HDL-C association shifts with menopause in the ARIC Study (Atherosclerosis 2008)Atherosclerosis · February 2008 5
• Combined CETP and ApoA-I genotypes span a 0.54 mmol/L range in HDL-C among Japanese women (Nutr Metab Cardiovasc Dis 2004)Nutr Metab Cardiovasc Dis · February 2004 5
• CETP activity rises 50% in one ABCA1-heterozygote kindred but not three others, alongside severe HDL abnormalities (Atherosclerosis 2003)Atherosclerosis · December 2003 5
• AICAR lowers blood glucose and insulin by suppressing endogenous glucose production, without correcting dyslipidaemia, in diabetic CETP-expressing KKAy mice (Diabetologia 2001)Diabetologia · December 2001 5
• CETP rises over time regardless of whether progestogen is added to low-dose estradiol in diabetic women (Diabet Med 2000)Diabet Med · April 2000 5
• CETP activity rises in the second trimester of pregnancy alongside falling hepatic lipase and rising estradiol (J Lipid Res 1996)J Lipid Res · February 1996 5
• Palmitic and lauric acid diets do not differ in CETP activity from each other, but lauric acid raises CETP activity above baseline (J Nutr 1995)J Nutr · March 1995 5
• Dietary cholesterol raises both LDL and HDL cholesterol in young women without changing fasting plasma CETP levels (Arterioscler Thromb Vasc Biol 1995)Arterioscler Thromb Vasc Biol · February 1995 5
• Tocilizumab decreases CETP activity by ~22% in 16 patients with rheumatoid arthritis (J Clin Lipidol 2026)J Clin Lipidol · August 2026 4
• Dalcetrapib does not affect the pharmacokinetics of a combined oral contraceptive in a crossover trial (Int J Clin Pharmacol Ther 2012)Int J Clin Pharmacol Ther · April 2012 4
• Low CETP activity and enhanced HDL2 paraoxonase found together in a patient with unusually low LDL-to-cholesterol ratio (Int J Mol Med 2010)Int J Mol Med · June 2010 4
• CETP TaqIB and I405V polymorphisms show sex-specific effects on postprandial triglycerides in familial hypercholesterolaemia (Lipids Health Dis 2009)Lipids Health Dis · June 2009 4
• CETP TaqIB genotype shows no link to preeclampsia or pregnancy lipid profile, unlike apoE (Eur J Obstet Gynecol Reprod Biol 2004)Eur J Obstet Gynecol Reprod Biol · January 2004 4
• High-trans-fat margarine trends toward higher CETP levels while lowering cholesterol esterification rate (J Lipid Res 2001)J Lipid Res · November 2001 4
• Continuous and cyclic HRT regimens both reshape HDL subclasses in postmenopausal women without altering CETP activity (Atherosclerosis 1997)Atherosclerosis · March 1997 4
• CETP activity peaks in the second trimester of pregnancy and tracks HDL-triglyceride accumulation (Clin Biochem 1994)Clin Biochem · February 1994 4
• CETP activity correlates with HDL triglyceride enrichment and reduced antioxidant capacity in postmenopausal women (Atherosclerosis 2004)Atherosclerosis · November 2004 3
• Egg-induced cholesterol hyperresponders show higher CETP and LCAT activity than hyporesponders (Metabolism 2004)Metabolism · June 2004 3
• Egg-diet hyperresponder premenopausal women show higher CETP alongside apoB and apoC-III (J Am Coll Nutr 2002)J Am Coll Nutr · June 2002 3